Selected Publications
AMP-activated protein kinase influences metabolic remodeling in H9c2 cells hypertrophied by arginine vasopressin. Saeedi R, Saran VV, Wu SS, Kume ES, Paulson K, Chan AP, Parsons HL, Wambolt RB, Dyck JR, Brownsey RW, Allard MF. Am J Physiol Heart Circ Physiol. 2009 Jun;296(6):H1822-32. Epub 2009 Apr 17.
Regulation of mitochondrial aconitase by phosphorylation in diabetic rat heart. Lin G, Brownsey RW, MacLeod KM. Cell Mol Life Sci. 2009 Mar;66(5):919-32.
Exercise restores endothelial function independently of weight loss or hyperglycaemic status in db/db mice. Moien-Afshari F, Ghosh S, Elmi S, Rahman MM, Sallam N, Khazaei M, Kieffer TJ, Brownsey RW, Laher I. Diabetologia. 2008 Jul;51(7):1327-37. Epub 2008 Apr 25.
Metabolic actions of metformin in the heart can occur by AMPK-independent mechanisms. Saeedi R, Parsons HL, Wambolt RB, Paulson K, Sharma V, Dyck JR, Brownsey RW, Allard MF. Am J Physiol Heart Circ Physiol. 2008 Jun;294(6):H2497-506. Epub 2008 Mar 28.
Regulation of acetyl-CoA carboxylase. Brownsey RW, Boone AN, Elliott JE, Kulpa JE, Lee WM. Biochem Soc Trans. 2006 Apr;34(Pt 2):223-7.
Inhibition of cyclic AMP dependent protein kinase by vanadyl sulfate. Jelveh KA, Zhande R, Brownsey RW. J Biol Inorg Chem. 2006 Apr;11(3):379-88. Epub 2006 Feb 28.
Inhibition of acetyl-CoA carboxylase isoforms by pyridoxal phosphate. Lee WM, Elliott JE, Brownsey RW. J Biol Chem. 280:41835-43 (2005)
Evidence for selective effects of vanadium on adipose cell metabolism involving actions on cAMP-dependent protein kinase. R.W. Brownsey and G.W. Dong. Biochemistry 153, 131-137 (1995)
Unique structural features and differential phosphorylation of the 280 kDa component (isozyme) of rat liver acetyl-CoA carboxylase. R. Winz, D. Hess, R. Aebersold and R.W. Brownsey J. Biol. Chem. 269, 2722-2731 (1994)
Introduction to metabolism. R.W. Brownsey. In: Biochemistry, by L.A. Moran, K.G. Scrimgeour, H.R. Horton, R.S. Ochs and J.D. Rawn. Second Edition (Moran and Scrimgeour, editors), Neil Patterson Publishers/Prentice-Hall, Engelwood Cliffs, NJ, pp 1-14 (1994)
CD14-dependent activation of protein kinase C and mitogen activated protein kinases (p42 and p44) in human monocytes treated with bacterial lipopolysaccharide. M.K. Liu, P. Herrera-Velit, R.W. Brownsey and N.E. Reiner Journal of Immunology 153, 2642-2652 (1994)
Analytical and micropreparative peptide mapping by high performance liquid chromatography/electrospray mass spectrometry of proteins purified by gel electrophoresis. D. Hess, T.C. Covey, R. Winz, R.W. Brownsey and R. Aebersold. Protein Science 2, 1342-1351 (1993)
Long-term effectiveness of oral vanadyl sulphate in streptozotocin-diabetic rats. M.C. Cam, R.A. Pederson, R.W. Brownsey and J.H. McNeill. Diabetologia 36, 218-224 (1993)
Evidence for a protein regulator from rat liver which activates acetyl-CoA carboxylase. K.A. Quayle, R.M. Denton and R.W. Brownsey. Biochem. J. 292, 74-85 (1993)
Acetyl CoA carboxylase. R.W. Brownsey and R.M. Denton. In: The Enzymes (3rd Edn.) Vol. XVIII, pp. 123-146. “Control by Phosphorylation”, Part B (P. Boyer and E.G. Krebs, eds.) Academic Press, New York (1987)
